Eliza Coupe is an American actress. Eliza Coupe is best known for her role as Denise "Jo" Mahoney in the medical comedy Scrubs, in which she became a regular for the ninth season.

Eliza Coupe graduated from Plymouth Regional High School. She has suffered from dyslexia since childhood but still was active in her high school`s award-winning theatre program. Coupe roles included Bonnie in Anything Goes and a Mundy sister in Dancing at Lughnasa. Eliza graduated from California Institute of the Arts.

Coupe currently stars in the ABC comedy series Happy Endings. The show finished its first season on May 25, 2011. The second season began airing on September 28, 2011.

Eliza lives in Los Angeles with her husband Randall Whittinghill.